The Researchers at the Peter Munk Cardiac Center, Toronto General Hospital, tested the effects of curcumin in mice with ‘Hypertrophy’ (enlarged hearts). They found that curcumin could prevent and reverse the condition and restore heart function, apart from reducing scar formation. The results of this study were published in the ˜Journal of Clinical Investigation, February issue.
The human clinical trials that were conducted, supported these findings, and the researchers are of the opinion that Curcumin-based treatments may prove to be a safe and inexpensive new option for patients suffering from heart enlargement.
Curcumin works directly in the cell nucleus by preventing abnormal unraveling of the chromosome when subjected to stress, and also preventing production of excessive abnormal proteins. This ability of curcumin to shut off one of the major switches at the chromosome source itself, where the enlargement and scarring genes are being turned on is quite impressive, said Dr. Peter Liu, Cardiologist at the Peter Munk Cardiac Center.
Liu said that irrespective of age or sex, the larger the heart, the higher is the risk for developing heart attacks or heart failure in the future. However, until the clinical trials are through, the patients are not recommended to take curcumin routinely. But, necessary initiatives such as reducing cholesterol and lowering blood pressure, exercising, and healthy eating can be started immediately.
According to the study, the clinical trials being carried-out on curcumin-based treatments for colorectal and pancreatic cancer are yielding promising results.